Big Sister

BUNDLE & SAVE WITH THE MONTHLY & CYSTERS CLUB | FREE USA SHIPPING ON ORDERS OVER $75

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@natural.dr.stephanie

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@bigsistersupplements

Banish PMS, tame PCOS
& say goodbye to hormonal acne

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PIMPLE PILLS

PIMPLE PILLS

with zinc & saw palmetto

1 MONTH SUPPLY

$34
PCOS POWDER

PCOS POWDER

with myo-inositol, licorice & peony

2 MONTH SUPPLY

$58
CRAMP STAMP

CRAMP STAMP

with cramp bark & red raspberry leaf

2 MONTH SUPPLY

$32
PMS PILLS

PMS PILLS

with vitex & DIM

1 MONTH SUPPLY

$38
the MONTHLY

the MONTHLY

cramp stamp & PMS pills x2

2 MONTH SUPPLY

$108$88
CYSTERS CLUB

CYSTERS CLUB

PCOS powder & pimple pills x2

2 MONTH SUPPLY

$126$96

HORMONE BALANCING
FORMULAS

Research- backed formulas for PMS, PCOS, PMDD, & hormonal acne.

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Hormone Balancing
Formulas

Research- backed formulas for PMS, PCOS, PMDD, & hormonal acne.

big sister hormone supplements
SHOP NOW
Diana G.
Life-Changer for My Cramps!
I used to be glued to my heating pad for the first two days of my period, but Cramp Stamp has been a game-changer. I take it at the first sign of cramps, and within 30 minutes, the pain fades. It’s much more effective than ibuprofen for me, and I love that it’s all-natural. Bonus: No drowsiness!
Jessica Z.
Definitely Helps
This definitely reduces my cramps. I used to take multiple painkillers every few hours, and now I can get through the day with just this supplement and maybe a heating pad. It’s been a huge improvement.
Emma P.
No More Emotional Rollercoaster!
My PMS used to be unbearable—crying over nothing, snapping at people, feeling totally out of control. After two cycles on PMS Pills, I feel so much more balanced. My moods don’t swing wildly, and my bloating has also noticeably gone down. I’ll never be without these! They also have a calming effect so are very nice to take to relax before bedtime.
Rhonda L.
Actually Works for My Irritability
I was skeptical, but PMS pills are a lifesaver. I usually turn into a monster the week before my period, but since taking these, I feel so much more level-headed. My boyfriend even noticed the difference before I did!
Isabella R.
Cleared My Jawline Acne in Two Months!
I’ve struggled with hormonal acne for years—big, painful cysts along my jawline that never fully went away. After using Pimple Pills for about six weeks, I noticed fewer breakouts, and by two months, my skin was the clearest it has been in years! I barely get a pimple now, and if I do, it heals fast.
Lena H.
It works, but You Need Patience
Pimple Pills works, but it’s not an overnight fix. I started seeing improvements around the 5-week mark, and my skin kept getting better from there. If you’re expecting instant results, you might be disappointed, but if you stick with it, it’s 100% worth it.
Maya G.
Amazing product for PCOS
I’m so happy I found PCOS Powder so I don’t have to take 15 different supplements a day. I love the all-natural ingredients and have noticed a significant change in my symptoms. I love that it includes holy basil! A rare product on the market for us PCOS girlies!
Rachel P.
My Periods Finally Came Back!
I have PCOS and hadn’t had a period in almost 5 months. I started taking PCOS Powder daily, and within six weeks, I got my period! My cycles have been getting more regular each month. It’s also helped with my sugar cravings, which is a huge plus.
Lauren B.
Helped My Fertility Journey
I’ve been trying to conceive for over a year with irregular cycles. After three months on PCOS Powder, my cycles regulated, and last month, I got my first positive pregnancy test! I can’t say for sure this is what did it, but I really believe it helped.
Nadia J.
Less Bloating & More Energy
I originally got PCOS powder for my irregular periods, but I was surprised to find that it also helped with bloating and my energy levels. I used to feel sluggish in the afternoons, but now I feel more stable throughout the day. My periods are still a little unpredictable, but they’re improving! I also really love the taste with hot water.

We use only the highest-grade, organic, raw botanicals and research-backed ingredients that are third-party tested to ensure quality, efficacy, and purity.

MORE ABOUT OUR QUALITY
big sister supplements essentials line

Your daily essentials

Daily vitamins & minerals essential for stress management, energy & hormonal balance

big sister supplements essentials line

FOUNDER + FORMULATOR​

Dr. Stephanie Nichols​

Licensed Naturopathic Doctor​

With nearly a decade of clinical experience and a passion for helping women overcome hormonal imbalances, Dr. Stephanie is excited and honored to empower women through BIG SISTER.

“I designed these unique formulas to address the most common hormonal issues women face today – comprehensive, natural solutions with noticeable results”-Dr. Stephanie

Dr. Stephanie has amassed millions of views with her educational videos, creating a supportive community on TikTok @natural.dr.stephanie and @bigsistersupplements

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